MKT & MKH Calculator

Upload your temperature or humidity logger data to calculate Mean Kinetic Temperature (MKT) and Mean Kinetic Humidity (MKH) for up to 100 loggers. 100% browser-based — your data never leaves your device.

Private by design: All calculations run in your browser. No data is uploaded, stored, or transmitted.

MKT

Mean Kinetic Temperature

MKT is a single calculated temperature that represents the cumulative thermal stress on a product over a period of variable storage conditions. Unlike a simple arithmetic average, MKT weights higher temperatures more heavily, reflecting the disproportionate impact of heat on product degradation.

Formula (USP <1150>)

MKT = (ΔH / R) / −ln[ (1/n) · Σ e−ΔH/(R·Ti) ]

Where ΔH = 83.144 kJ/mol (activation energy), R = 8.31446 J/mol·K, Ti = temperature in Kelvin, n = number of readings.

Commonly used for

  • • Stability studies and shelf-life assessment
  • • Warehouse and cold room qualification
  • • Transport lane validation (GDP)
  • • Product release and excursion review
MKH

Mean Kinetic Humidity

MKH applies the same kinetic weighting concept to relative humidity, producing a single value that represents the cumulative moisture exposure of a product. It is particularly relevant for moisture-sensitive products where humidity fluctuations affect stability and packaging integrity.

Formula (Arrhenius-style)

MKH = −(ΔH / R) / ln[ (1/n) · Σ e−ΔH/(R·RHi) ]

Where ΔH = 44.0 kJ/mol (enthalpy of water vaporisation at ~25°C), R = 8.31446 J/mol·K, RHi = relative humidity in %.

Commonly used for

  • • Moisture-sensitive tablet and capsule storage
  • • Biologics and vaccine packaging assessment
  • • Long-term stability program support
  • • Humidity-controlled chamber qualification

Note on MKH: Unlike MKT, there is no universally standardised MKH equation in regulatory guidance (e.g., USP). This calculator uses an Arrhenius-style kinetic approach mirroring the MKT formula, with the enthalpy of vaporisation of water as the weighting factor. Results should be interpreted as indicative and reviewed in the context of product-specific stability data.

Run a Calculation

Step 1 — Choose calculation mode

Step 2 — Download a CSV template

Required columns: datetime + at least one of temperature / humidity. Multi-logger files also need a logger_id column. Datetime formats accepted: ISO 8601 (2025-01-01 08:00:00), US/EU short formats with AM/PM.

Step 3 — Optional acceptance criteria

Step 4 — Upload your CSV file

Drop CSV file here or click to browse

Maximum 100 loggers · All processing in your browser

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